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N-De-Boc-N-Formyl Cabazitaxel

N° de SZ CAT SZ-C056038
Número CAS NA
Mol.F. C41H49NO13
Peso Molecular 763.8
Status de Fatura Custom Synthesis


Nome Químico: (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-9-(((2R,3S)-3-Formamido-2-hydroxy-3-phenylpropanoyl)oxy)-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl Benzoate

Sinônimo: Cabazitaxel N-Formyl Impurity

Sorrisos: O=C(O[C@@H]([C@@]1([H])[C@@]2(C)[C@@H](OC)C[C@@]3([H])OC[C@]31OC(C)=O)[C@]4(O)C[C@H](OC([C@H](O)[C@@H](NC=O)C5=CC=CC=C5)=O)C(C)=C(C4(C)C)[C@@H](OC)C2=O)C6=CC=CC=C6

Inchi: InChI=1S/C50H65NO16/c1-27-31(63-42(56)36(53)35(29-20-16-14-17-21-29)51(43(57)66-45(3,4)5)44(58)67-46(6,7)8)25-50(59)40(64-41(55)30-22-18-15-19-23-30)38-48(11,39(54)37(61-13)34(27)47(50,9)10)32(60-12)24-33-49(38,26-62-33)65-28(2)52/h14-23,31-33,35-38,40,53,59H,24-26H2,1-13H3/t31-,32-,33+,35-,36+,37+,38-,40-,48+,49-,50+/m0/s1

Development and Validation of a Stability-​indicating HPLC Method for the Analysis of Cabazitaxel in Jevtana Concentrate-​solvent Leftover Samples
By Arnamo, Hedvig; Hillebrand, Michel J. X.; Huitema, Alwin D. R.; Nuijen, Bastiaan; Rosing, Hilde; Beijnen, Jos H.
From Current Pharmaceutical Analysis (2021), 17(6), 691-701
 
Development and Validation of a Stability-​Indicating HPLC Method for the Determination of the Impurities in Cabazitaxel
By Li, Chengyan; Lan, Gongjian; Jiang, Jinyuan; Sun, Mingjie; Hang, Taijun
From Chromatographia (2015), 78(11-12), 825-831
 
Development and validation of a stability-​indicating liquid chromatographic method for the assay of cabazitaxel
By Mathrusri Annapurna, M.; Venkatesh, B.; Pramadvara, K.; Hemchand, S.
From Chemical Science Transactions (2014), 3(2), 854-860, 7 pp.