Nome Químico: 8-fluoro-2,2-dimethyl-9-(4-methylpiperazin-1-yl)-6-oxo-5,6-dihydro-2H,4H-oxazolo[5,4,3-ij]quinoline-5-carboxylic acid
Sorrisos: FC1=C(N2CCN(C)CC2)C(OC3(C)C)=C(N3CC(C(O)=O)C4=O)C4=C1
Inchi: InChI=1S/C14H22N6O4.ClH/c1-8(2)5-9(15)13(22)24-4-3-23-7-20-6-17-10-11(20)18-14(16)19-12(10)21;/h6,8-9H,3-5,7,15H2,1-2H3,(H3,16,18,19,21);1H/t9-;/m0./s1
In silico and in vitro genotoxicity evaluation of levofloxacin n-oxide, an impurity in levofloxacin
Qingfen Zhu1,2, Tao Li2 , Jun Li2 , Ming Guo2 , Weijian Wang2 , and Xiumei Zhang
Toxicology Mechanisms and Methods, 2012; 22(3): 225–230
Identification, Isolation and Characterization of New Process-related Impurities in Levofloxacin
Kishor More* , Leena Gupta, Brajesh Sharma, Prashant Patil, Dattatray Govare
Der Pharma Chemica, 2017, 9(12):7-13
An integrated approach for detection and characterization of the trace impurities in levofloxacin using liquid chromatography– tandem mass spectrometry
Ya-Jie Zheng1 , Jiu-Ming He1 , Rui-Ping Zhang1 , Yu-Cheng Wang2 , Ju-Xian Wang2 , Hui-Qing Wang1 , Yan Wu1 , Wen-Yi He1 and Zeper Abliz
Rapid Commun. Mass Spectrom. 2014, 28, 1164–1174
Analyses of Levofloxacin Adsorption on Pretreated Barley Straw with Respect to Temperature: Kinetics, π–π Electron-Donor–Acceptor Interaction and Site Energy Distribution
Bei Yan, Catherine Hui Niu, and Jian Wang
Environ. Sci. Technol. 2017, 51, 14, 8048–8056
Rapid chiral separation and impurity determination of levofloxacin by ligand-exchange chromatography
Hongyuan Yan, Kyung Ho Row
Analytica Chimica Acta 584 (2007) 160–165
