Nome Químico: 4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-ol
Sinônimo: O-Desmorpholinopropyl Gefitinib ;
Sorrisos: ClC1=C(F)C=CC(NC2=NC=NC3=CC(OC)=C(O)C=C23)=C1
Inchi: InChI=1S/C21H20Cl3FN4O2/c22-15-10-13(2-3-16(15)25)28-21-14-11-17(18(23)19(24)20(14)26-12-27-21)31-7-1-4-29-5-8-30-9-6-29/h2-3,10-12H,1,4-9H2,(H,26,27,28)
Identification, characterization and HPLC quantification of formulation-related impurities of honokiol, an antitumor natural drug candidate in clinical trials
Wenshuang Wu 1,2, # , Ming-Hai Tang2, # , Huan Tang 2 , Kai Chen 2,3 , Jie Fu 4 , Lun Wang 2,3 , Lin-Lin Xue 2 , Aihua Peng 2 , Haoyu Ye 2, 4* , Li-Juan Chen
Journal of Pharmaceutical and Biomedical Analysis Volume 153, 10 May 2018, Pages 186-192
Separation and Estimation of Process-Related Impurities of Gefitinib by Reverse-Phase High-Performance Liquid Chromatography
Karunakara A. Chandrashekara, Aparna Udupi, Chandrasekara G. Reddy
Journal of Chromatographic Science, Volume 52, Issue 8, September 2014, Pages 799–805