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Decitabine Alpha-Isomer(Hydrate)

N° de SZ CAT SZ-D019014
Número CAS NA
Mol.F. C8H12N4O4 : H2O
Peso Molecular 228.2 : 18.0
Status de Fatura In Stock


Nome Químico: 4-Amino-1-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one hydrate

Sorrisos: O=C1N([C@H]2O[C@H](CO)[C@@H](O)C2)C=NC(N)=N1.O

Inchi: InChI=1S/C46H64N14O13S2/c47-34(62)20-31-43(71)59-32(45(73)60-17-5-9-33(60)44(72)56-27(8-4-16-52-46(50)51)39(67)53-22-35(48)63)23-74-75-36(49)21-37(64)54-29(19-25-10-12-26(61)13-11-25)41(69)57-30(18-24-6-2-1-3-7-24)42(70)55-28(40(68)58-31)14-15-38(65)66/h1-3,6-7,10-13,27-33,36,61H,4-5,8-9,14-23,49H2,(H2,47,62)(H2,48,63)(H,53,67)(H,54,64)(H,55,70)(H,56,72)(H,57,69)(H,58,68)(H,59,71)(H,65,66)(H4,50,51,52)/t27-,28?,29-,30-,31?,32-,33-,36?/m0/s1

Development, validation, and clinical application of a high-performance liquid chromatography-tandem mass spectrometry assay for the quantifica0074ion of total intracellular -decitabine nucleotides and genomic DNA incorporated -decitabine and 5-methyl-2 -deoxycytidine
Jeroen Roosendaal , Hilde Rosinga, Luc Lucas a, Aram Oganesianc, Jan H.M. Schellens b,d,e, Jos H. Beijnen
Journal of Pharmaceutical and Biomedical Analysis 164 (2019) 16–26
 
Isolation, characterization, and properties of a labile hydrolysis product of the antitumor nucleoside, 5-azacytidine
John A. Beisler
J. Med. Chem. 1978, 21, 2, 204–208
 
Stability indicating RP-HPLC Method Devlopment and Validation of Decitabine Drug in Formulation
Glory hepsiba1 *, Dr.B.B.Teja2 , K.Ashok kumar1 , Y.Ravindra reddy
International Journal of PharmTech Research CODEN (USA): IJPRIF Vol. 3, No.1, pp 237-243,