化学名称: 7-[4-[4-(2,3-Dichlorophenyl)-1-oxido-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone
异名: Aripiprazole N1-Oxide , Aripiprazole USP Related Compound F,
微笑: O=C1NC2=C(C=CC(OCCCC[N+]3([O-])CCN(C4=CC=CC(Cl)=C4Cl)CC3)=C2)CC1
印地语: InChI=1S/C23H25Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-9,16H,1-2,10-15H2,(H,26,29)
Formulation of aripiprazole-loaded pH-modulated solid dispersions via hot-melt extrusion technology: In vitro and In vivo studies
Haley McFall1 , Sandeep Sarabu1 , Vijaykumar Shankar1 , Suresh Bandari1 , S. Narasimha Murthy1 , Karl Kolter2 , Nigel Langley3 , Dong Wuk Kim4**, Michael A. Repka
International Journal of Pharmaceutics Volume 554, 10 January 2019, Pages 302-311
Molecular determinants of the intrinsic efficacy of the antipsychotic aripiprazole
Carmen Klein Herenbrink, Ravi Verma, Herman D Lim, Anitha Kopinathan, Alastair Keen, Jeremy Shonberg, Christopher J. Draper-Joyce, Peter J. Scammells, Arthur Christopoulos, Jonathan A Javitch, Ben Capuano, Lei Shi, and J Robert Lane
ACS Chem. Biol. 2019, 14, 8, 1780–1792
Identification of Degradation Impurities in Aripiprazole Oral Solution Using LC-MS and Development of Validated Stability Indicating Method for Assay and Content of Two Preservatives by RP-HPLC
M. V. V. N. Murali Krishna, Sumathi V. Rao & N. V. S. Venugopal
European Journal of Chemistry 2010, 1(1), 20-27
Development of stability indicating, validated HPLC method for quantitative determination of Aripiprazole and its impurities
Nandini R. Pai*, Deepnandan S. Dubhashi
Der Pharmacia Lettre, 2010, 2(4): 1-10