Nome Químico: Ethyl (1Z)-N-[[2-[4-[[(4-fluorophenyl)methyl]carbamoyl]-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl]propan-2-yl]oxamoyl]ethanehydrazonate (as per EP); Ethyl (Z)-N-{2-[(2-{4-[(4-fluorobenzyl)carbamoyl]-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl}propan-2-yl)amino]-2-oxoacetyl}acetohydrazonate (as per USP)
Sinônimo: Raltegravir Z-ethoxyacethydrazone analog
Sorrisos: O=C(C(NC(C)(C)C(N1C)=NC(C(NCC2=CC=C(F)C=C2)=O)=C(O)C1=O)=O)N/N=C(C)\OCC
Inchi: InChI=1S/C22H27FN6O6/c1-6-35-12(2)27-28-19(33)18(32)26-22(3,4)21-25-15(16(30)20(34)29(21)5)17(31)24-11-13-7-9-14(23)10-8-13/h7-10,30H,6,11H2,1-5H3,(H,24,31)(H,26,32)(H,28,33)/b27-12+
Development and validation of stability indicating RP-HPLC assay method of raltegravir in tablet dosage forms
By Shirisha, V.; Sairaju, B.; Illendula, Santhosh; Dutt, K. Rajeswar
From World Journal of Pharmacy and Pharmaceutical Sciences (2019), 8(10), 668-692
Stability indicating reverse-phase high performance liquid chromatography method for the determination of raltegravir in bulk and pharmaceutical formulation
By Annapurna, Mukthinuthalapati Mathrusri; Teja, Gunnam Ravi; Hemchand, S.; Babu, R. Ravi Chandra
From International Journal of Green Pharmacy (2018), 12(1Suppl.), S177-S180
Development and validation of RP-HPLC method for determination of raltegravir and its impurities in bulk drug and dosage forms
By Balaji, M.; AppaRao, K. M. Ch.; Ramakrishna, K.; Srinivasarao, V.
From Pharma Science Monitor (2014), 5(3Suppl.1), 187-196, 10 pp.