Chemical Name: 2-Amino-4-chloro-N-(2-methylphenyl)-5-sulfamoylbenzamide (as per EP)
Synonym: Metolazone USP Related Compound B ; Metolazone benzamide analog
Smiles: O=C(C1=CC([S](N)(=O)=O)=C(Cl)C=C1N)NC(C=CC=C2)=C2C
Inchi: InChI=1S/C16H14ClN3O3S/c1-9-5-3-4-6-14(9)20-10(2)19-13-8-12(17)15(24(18,22)23)7-11(13)16(20)21/h3-8H,1-2H3,(H2,18,22,23)
Determination of a Metolazone metabolite in human urine by high‐performance liquid chromatography/diode‐array detection, high‐performance liquid chromatography/electrospray ionization mass spectrometry and gas chromatography/mass spectrometry
Yunje Kim Sungil Kim Myungsoo Kim Won Lee
Rapid Commun. Mass Spectrom. 2004; 18: 917–922
Analytical method development and validation of simultaneous estimation of Metolazone and Spironolactone in bulk and pharmaceutical dosage form by RP-HPLC
G.Pallavi , A.Ravi Kumar
Indian Journal of Research in Pharmacy and Biotechnology 2(6) ; 2320 – 3471