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Desonide Impurity 2

Picture of Desonide Impurity 2
SZ CAT No SZ-D008017
CAS No NA
Mol.F. C24H30O5
Mol.Wt. 398.5
Inv. Status In Stock


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SynZeal product information given on this website is as per the existing understanding while publishing the details on website. The customer is responsible for assessing the accuracy of the information at the time of actual purchase.

SynZeal will update these details as per new development or finding in product specification without further noticed.

Chemical Name: Pregna-1,4,9(11)-triene-3,20-dione, 16α,17,21-trihydroxy-, cyclic 16,17-acetal with acetone (7CI,8CI); (16α)-21-Hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4,9(11)-triene-3,20-dione; 21-Hydroxy-16α,17α-(isopropylidenedioxy)pregna-1,4,9(11)triene-3,20-dione; Pregna-​1,​4,​9(11)​-​triene-​3,​20-​dione, 21-​hydroxy-​16,​17-​[(1-​methylethylidene)​bis(oxy)​]​-​, (16α)​-;

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C1C=C[C@@]2(C)C(CCC3C2=CC[C@@]4(C)C3C[C@H]5[C@]4(OC(C)(C)O5)C(CO)=O)=C1

Desonide Impurity 2 is chemically Pregna-1,4,9(11)-triene-3,20-dione, 16α,17,21-trihydroxy-, cyclic 16,17-acetal with acetone (7CI,8CI); (16α)-21-Hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4,9(11)-triene-3,20-dione; 21-Hydroxy-16α,17α-(isopropylidenedioxy)pregna-1,4,9(11)triene-3,20-dione; Pregna-​1,​4,​9(11)​-​triene-​3,​20-​dione, 21-​hydroxy-​16,​17-​[(1-​methylethylidene)​bis(oxy)​]​-​, (16α)​-;. Desonide Impurity 2 is supplied with detailed characterization data compliant with regulatory guideline. Desonide Impurity 2 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Desonide.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Development of a novel HPLC method for the determination of the impurities in desonide cream and characterization of its impurities by 2D LC-IT-TOF MS
Jian Wanga,b, Shuxian Zhenga, Yu Xua, Haiyan Huc, Minji Shenc, Lan Tang
Journal of Pharmaceutical and Biomedical Analysis 161 (2018) 399–406
 
Studies on the Stability of Corticosteroids: Degradation of Clobetasol Propionate, Desonide and Hydrocortisone in Topical Formulations by HPLC and UPLC-MS/MS
Kishore Kumar Hotha, Subathra Ramamoorthy1, Hiren Patel
American Journal of Analytical Chemistry, 2020, 11, 147-171

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