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Aripiprazole Inhouse Impurity G

N° de SZ CAT SZ-A001056
Número CAS 129722-20-9
Mol.F. C23H27Cl2N3O2
Peso Molecular 448.4
Status de Fatura In Stock


Nome Químico: 7-[4-{4-(3,5-Dichlorophenyl)-1-piperazinyl} butoxy]-3,4-Dihydro 2(1H)- quinolinone

Sorrisos: O=C1NC2=C(C=CC(OCCCCN3CCN(C4=CC(Cl)=CC(Cl)=C4)CC3)=C2)CC1

Inchi: InChI=1S/C25H33NO7/c1-13(27)26-25(21(32)12-33-14(2)28)20(31)10-18-17-6-5-15-9-16(29)7-8-23(15,3)22(17)19(30)11-24(18,25)4/h7-9,17-20,22,30-31H,5-6,10-12H2,1-4H3,(H,26,27)/t17?,18?,19-,20+,22?,23-,24-,25-/m0/s1

Formulation of aripiprazole-loaded pH-modulated solid dispersions via hot-melt extrusion technology: In vitro and In vivo studies
Haley McFall1 , Sandeep Sarabu1 , Vijaykumar Shankar1 , Suresh Bandari1 , S. Narasimha Murthy1 , Karl Kolter2 , Nigel Langley3 , Dong Wuk Kim4**, Michael A. Repka
International Journal of Pharmaceutics Volume 554, 10 January 2019, Pages 302-311
 
Molecular determinants of the intrinsic efficacy of the antipsychotic aripiprazole
Carmen Klein Herenbrink, Ravi Verma, Herman D Lim, Anitha Kopinathan, Alastair Keen, Jeremy Shonberg, Christopher J. Draper-Joyce, Peter J. Scammells, Arthur Christopoulos, Jonathan A Javitch, Ben Capuano, Lei Shi, and J Robert Lane
ACS Chem. Biol. 2019, 14, 8, 1780–1792
 
Identification of Degradation Impurities in Aripiprazole Oral Solution Using LC-MS and Development of Validated Stability Indicating Method for Assay and Content of Two Preservatives by RP-HPLC
M. V. V. N. Murali Krishna, Sumathi V. Rao & N. V. S. Venugopal
European Journal of Chemistry 2010, 1(1), 20-27
 
Development of stability indicating, validated HPLC method for quantitative determination of Aripiprazole and its impurities
Nandini R. Pai*, Deepnandan S. Dubhashi
Der Pharmacia Lettre, 2010, 2(4): 1-10