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Aripiprazole Impurity 2

N° de SZ CAT SZ-A001032
Número CAS 1424857-93-1
Mol.F. C14H18Cl2N2 
Peso Molecular 285.2
Status de Fatura Custom Synthesis


Nome Químico: 1-(3-Buten-1-yl)-4-(2,3-dichlorophenyl)-piperazine;

Sorrisos: C=CCCN1CCN(C2=CC=CC(Cl)=C2Cl)CC1

Inchi: InChI=1S/C13H16BrNO2/c14-8-1-2-9-17-12-5-3-4-11-10(12)6-7-13(16)15-11/h3-5H,1-2,6-9H2,(H,15,16)

Formulation of aripiprazole-loaded pH-modulated solid dispersions via hot-melt extrusion technology: In vitro and In vivo studies
Haley McFall1 , Sandeep Sarabu1 , Vijaykumar Shankar1 , Suresh Bandari1 , S. Narasimha Murthy1 , Karl Kolter2 , Nigel Langley3 , Dong Wuk Kim4**, Michael A. Repka
International Journal of Pharmaceutics Volume 554, 10 January 2019, Pages 302-311
 
Molecular determinants of the intrinsic efficacy of the antipsychotic aripiprazole
Carmen Klein Herenbrink, Ravi Verma, Herman D Lim, Anitha Kopinathan, Alastair Keen, Jeremy Shonberg, Christopher J. Draper-Joyce, Peter J. Scammells, Arthur Christopoulos, Jonathan A Javitch, Ben Capuano, Lei Shi, and J Robert Lane
ACS Chem. Biol. 2019, 14, 8, 1780–1792
 
Identification of Degradation Impurities in Aripiprazole Oral Solution Using LC-MS and Development of Validated Stability Indicating Method for Assay and Content of Two Preservatives by RP-HPLC
M. V. V. N. Murali Krishna, Sumathi V. Rao & N. V. S. Venugopal
European Journal of Chemistry 2010, 1(1), 20-27
 
Development of stability indicating, validated HPLC method for quantitative determination of Aripiprazole and its impurities
Nandini R. Pai*, Deepnandan S. Dubhashi
Der Pharmacia Lettre, 2010, 2(4): 1-10