Nome Químico: (2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(3-fluorophenyl)morpholine hydrochloride
Sorrisos: FC1=CC([C@@H]2NCCO[C@@H]2O[C@@H](C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)C)=CC=C1.Cl
Application of analytical quality by design principles for the determination of alkyl p-toluenesulfonates impurities in Aprepitant by HPLC. Validation using total-error concept
Constantinos K. Zacharis, Elli Vastardi
Journal of Pharmaceutical and Biomedical Analysis Volume 150, 20 February 2018, Pages 152-161
Characterization and Quantitation of Aprepitant Drug Substance Polymorphs by Attenuated Total Reflectance Fourier Transform Infrared Spectroscopy
Roy Helmy,* George X. Zhou, Yadan W. Chen, Louis Crocker, Tao Wang, Robert M. Wenslow, Jr., and Anant Vailaya*
Anal. Chem. 2003, 75, 605-611
Development and Optimization of Liquid Chromatography Analytical Methods by Using AQbD Principles: Overview and Recent Advances
Tim Tome,†,Nina Ž igart, Zdenko Č asar,, and AlešObreza
Org. Process Res. Dev. 2019, 23, 1784−1802