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3-Descarbonitrile 3-Acetamido Saxagliptin

N° de SZ CAT SZ-S005016
Número CAS 1496712-39-0
Mol.F. C18H27N3O3
Peso Molecular 333.4
Status de Fatura In Stock
Rel. CAS No 2173146-02-4 (HCl salt)

Nome Químico: (1S,3S,5S)-2-[(2S)-2-Amino-2-(3-hydroxytricyclo [,7]dec-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carboxamide; 2-​Azabicyclo[3.1.0]​hexane-​3-​carboxamide, 2-​[(2S)​-​2-​amino-​2-​(3-​hydroxytricyclo[3.3.​1.13,​7]​dec-​1-​yl)​acetyl]​-​, (1S,​3S,​5S)​-; (1S,3S,5S)-2-((S)-2-amino-2-((1r,3R,5R,7S)-3-hydroxyadamantan-1-yl)acetyl)-2-azabicyclo[3.1.0]hexane-3-carboxamide

Preparation of Saxagliptin, a Novel DPP-IV Inhibitor
Scott A. Savage,* Gregory S. Jones, Sergei Kolotuchin, Shelly Ann Ramrattan, Truc Vu, and Robert E. Waltermire
Organic Process Research & Development 2009, 13, 1169–1176
Spectrophotometric and spectrofluorimetric methods for the determination of saxagliptin and vildagliptin in bulk and pharmaceutical preparations
Marwa S.Moneeb
Bulletin of Faculty of Pharmacy, Cairo University Volume 51, Issue 2, December 2013, Pages 139-150
Understanding and Kinetic Modeling of Complex Degradation Pathways in the Solid Dosage Form: The Case of Saxagliptin
Blaž Robnik,1,2 Blaž Likozar,3 Baifan Wang,3,† Tijana Stanić Ljubin,1 and Zdenko Časar
Pharmaceutics. 2019 Sep; 11(9): 452.
Reversed-phase liquid chromatography with mass detection and characterization of saxagliptin degradation related impurities
F. I. Farooqui* and R. B. Kakde
Journal of Chemical and Pharmaceutical Research, 2016, 8(7):509-514
Development and Validation of Novel Stability- Indicating LC Method for the Determination of Saxagliptin and Metformin
Sachin Bhanudas Gurav*, Neela Manish Bhatia
Indian Journal of Pharmaceutical Education and Research |Vol 54 | Issue 2 (Suppl) | Apr-Jun, 2020