Chemical Name: 4-{5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-yl}butanoic acid monohydrochloride (as per USP)
Synonym: Cytostasan ; Ribomustin ; Treanda
Smiles: CN1C(C=C2)=C(N=C1CCCC(O)=O)C=C2N(CCCl)CCCl.Cl
Inchi: InChI=1S/2C10H13FN2O5/c2*1-10(11)7(16)5(4-14)18-8(10)13-3-2-6(15)12-9(13)17/h2*2-3,5,7-8,14,16H,4H2,1H3,(H,12,15,17)/t5-,7-,8+,10-;5-,7-,8-,10-/m00/s1
Polymorphic forms of bendamustine hydrochloride: crystal structure, thermal properties and stability at ambient conditions
By Gaztanaga, Pablo; Baggio, Ricardo; Vega, Daniel Roberto
From Acta Crystallographica, Section B: Structural Science, Crystal Engineering and Materials (2019), 75(6), 933-941
Development and validation of a stability-indicating rp-hplc method for the determination of bendamustine in raw material and finished product
By Dhananjaya, G.; Naveen, M.; Pathi, P. Janaki; Raghuram, J.; Raju, N. Appala
From World Journal of Pharmaceutical Research (2018), 7(18), 1172-1187
Novel validated RP-HPLC method for bendamustine hydrochloride based on ion-pair chromatography: application in determining infusion stability and pharmacokinetics
By Singh, Yuvraj; Chandrashekar, Anumandla; Pawar, Vivek K.; Saravanakumar, Veeramuthu; Meher, Jayagopal; Raval, Kavit; Singh, Pankaj; Kumar, R. Dinesh; Chourasia, Manish K.
From Journal of Chromatographic Science (2017), 55(1), 30-39
Stability- indicating novel HPLC method for estimation of Bendamustine in pharmaceutical forms
By Reddy, Gade Srinivas; Reddy, S. L. N. Prasad; Reddy, L. Shiva kumar
From American Journal of PharmTech Research (2016), 6(2), 343-357